禽包涵体肝炎（Avian inclusion body hepatitis）.doc

禽包涵体肝炎（Avian inclusion body hepatitis） Avian inclusion body hepatitis Avian inclusion body hepatitis is an acute infectious disease of chicks caused by I avian adenovirus. It is characterized by hepatitis, the formation of intranuclear inclusions in liver cells, anemia and muscle bleeding. Avian adenoviruses known to have 12 serotypes are related to the disease. [clinical symptoms] a healthy chicken group suddenly develops and dies at 3~5 days, then stops quickly and lasts for 2~3 weeks. The incidence of disease was low, the chicken feather curled posture, shaggy, manifestation of anemia, jaundice, weakness and prostration. Symptomatic chickens usually die within a few hours. Light chicken can recover after a few days, the majority of asymptomatic infected chickens weight loss, feed utilization rate decreased, showing a transient egg reduction. Adult chicken infections usually do not show clinical signs, but can detect antibodies in the blood. [] the main changes of pathological changes of anemia, jaundice, hepatomegaly, pale, crisp, surface spots varying degrees of bleeding or hemorrhage, necrosis and some visible to the size of the liver, fade is pale brown to yellow. The long course of disease liver atrophy. Pathological examination showed intranuclear inclusion bodies in hepatocytes. The kidneys are swollen and pale. The membranes are scattered with punctate hemorrhages and urate deposits are found in the tubules. In some cases still visible spleen and bursa atrophy, bone marrow lesions, bone marrow is pink or brown, occasionally grayish white jelly. Obvious bleeding was seen in the subcutaneous, pectoral, leg, intestinal, and other organs. [in] kind of pathological changes in differential diagnosis of inclusion body hepatitis mainly concentrated in liver and duodenum, liver showed acute and degenerative arthritis and inflammation changes in highly degenerated liver nuclei appeared basophilic or eosinophilic inclusion; duodenum showed acute hemorrhagic inflammat