第十二章 蛋白质的酶促降解及氨基酸代谢（The twelfth chapter is the enzymatic degradation and amino acid metabolism of proteins）.docVIP

第十二章 蛋白质的酶促降解及氨基酸代谢（The twelfth chapter is the enzymatic degradation and amino acid metabolism of proteins） The twelfth chapter is the enzymatic degradation and amino acid metabolism of proteins Section 1 enzymatic degradation of proteins The decomposition of second amino acids Transformation of third amino acid decomposition products Biosynthesis of amino acids in fourth amino acids Section 1 enzymatic degradation of proteins Amino acids are the basic unit of protein, protein intake of the body after the first digestion into various free amino acids and small peptides in the digestive tract, in order to supply the bodys own synthesis of various protein to supplement the loss of body protein. Digestive region: begins at the stomach, mainly in the small intestine The specificity of several proteases in the digestive tract Catabolism of second amino acids Metabolism of amino acids Three, the decarboxylation of amino acids Two. Deamination of amino acids Two. Deamination of amino acids 4. Non oxidative deamination 1. Oxidative deamination 2, the role and significance of amino transfer 3 、 combined deamination 1. Oxidative deamination The process of deamination of amino acids to catalyze the deamination of amino acids to produce the corresponding alpha keto acids is called oxidative deamination. There are two main types: glutamate - glutaric acid 2, the role of amino Transaminase (CoA: pyridoxal-5-phosphate) The transaminase catalyzed transfer of alpha amino acid to the keto carbon atom alpha keto acid, the original alpha amino acids corresponding - keto acid, while the original alpha keto acid formed the corresponding alpha amino acids, which said the change for transamination or amino shift. Transaminase There are a variety of transaminase in the body, with specificity, and the amino acids and alpha keto acid between the role of ammonia can only be catalyzed by a specific transaminase. Alpha ketoglutaric acid, oxaloacetic acid, pyruvate transaminase as amino receptor