解酒护肝饮对酒精性肝损伤大鼠血清和肝组织mda、gsh的影响（The influence of Kang Yin Jian Yin on serum and liver tissue MDA and GSH in rats with alcoholic liver injury）.doc

解酒护肝饮对酒精性肝损伤大鼠血清和肝组织mda、gsh的影响（The influence of Kang Yin Jian Yin on serum and liver tissue MDA and GSH in rats with alcoholic liver injury） The influence of Kang Yin Jian Yin on serum and liver tissue MDA and GSH in rats with alcoholic liver injury Update Date: 2009-05-08 click: Yang Muxiang, Tian Yuanxiang, Yao Shukun, Li Rongyan, Ji Zhi, Cao Gang, Xu Huiming, Ma Quanqing Abstract: Objective: To observe the effect of Kang Jie Yin Decoction on MDA and GSH in serum and liver tissue of rats with alcoholic liver injury, and to investigate the preventive and therapeutic effects on liver injury induced by alcohol. Methods: Yiganling, pueravia flower soup as control by perfusing stomach model, detect the content of MDA and GSH in serum and liver tissue of rats in each group were preventive medication and treatment after. Results: the drug prevention results show that the JHD model and Ge in serum and liver tissue of rat MDA flower haejangguk, Yiganling significantly reducing the high dose, but prevents the depletion of GSH, increase the activity of GSH is superior to the two control groups. High dose and low dose have dose effect relationship. The therapeutic result showed that the high and low doses of the liver and liver can reduce the content of MDA in the serum and liver tissue of the model rats, prevent the depletion of GSH and increase the activity of GSH, and have dose effect relationship. Conclusion: Jiejiuhugan decoction can inhibit peroxidation by reducing the content of MDA in blood serum and liver MDA to reduce body injury; also increased the activity of GSH, increase the content of GSH, anti peroxidation, can effectively prevent alcoholic liver injury, and the effect is better than that of Yiganling and pueravia flower soup. Keywords alcoholic liver injury; sobering up liver drink; rats; prevention; treatment; malondialdehyde; glutathione; CLC Code: R 285.5, document identifier code: A, article number: 1007-5615 (2000) 04-0001-06 The, Effect, of, Anti-Alcoho