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酒精肝的治疗方法(Treatment of alcoholic liver)
酒精肝的治疗方法(Treatment of alcoholic liver)
Alcoholic liver disease is caused by long periods of heavy drinking (alcohol). After ethanol enters the liver cell, it is oxidized to acetaldehyde through a series of enzymes. Excessive drinking, a large number of acetaldehyde on the liver cells have obvious toxicity. Directly or indirectly lead to liver cell degeneration, necrosis, and fibrosis, which can develop into cirrhosis in severe cases.
The pathogenesis of alcoholic fatty liver has been proved in recent years:
(1) free fatty acids enter the blood too much.
(2) the new synthesis of hepatic fatty acids increased.
(3) decrease in oxidation of hepatic fatty acids.
(4) three diacylglycerol synthesis.
(5) intracellular lipoprotein release disorder in hepatocytes.
Patients with alcoholic liver disease often appear early: significant weight loss, loss of appetite, nausea and vomiting, general malaise, fever, abdominal pain and diarrhea, and upper gastrointestinal bleeding.
Alcoholic liver not only affect the absorption and synthesis of protein and vitamin (malnutrition), malnutrition has become secondary factors of hepatic cell damage further, interaction can eventually lead to liver cell fatty infiltration, inflammation, necrosis, the occurrence of liver cirrhosis. If it is allowed to develop, fibrosis and cirrhosis are inevitable, and many complications can occur. These complications are often a risk factor for alcoholic liver failure:
1. upper digestive tract hemorrhage: portal hypertension caused by hepatic alcohol occurred, upper gastrointestinal bleeding, also may be due to acute gastric erosion, ulcer or esophageal variceal bleeding (EVB), if you can not deal with timely and effective, will shock the crisis of life and death risk.
2.: alcoholic liver ascites and infection because of electrolyte, osmotic pressure, nutrition and other factors lead to the emergence of a large number of ascites, similar to liver cirrhosis and hepatocellular carcinoma in patients with ascite
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