阿莫西林的临床应用（Clinical application of amoxicillin）.docVIP

阿莫西林的临床应用（Clinical application of amoxicillin） The clinical application of amoxicillin.Txt love feeling empty empty, his wandering in the street; empty empty money, single paying in the work; it empty empty industry, want to go mad; empty empty bowl basin, the life force is not easy. In a word, All is void! [keyword] Western medicine; amoxicillin; clinical application [Abstract] the physical and chemical characteristics, pharmacological mechanism and clinical application of amoxicillin were introduced in detail in this paper. The antibacterial action, clinical application and attention in application of amoxicillin are emphasized. It is hoped that this study can provide guidance for the practical application of amoxicillin in clinical practice, and it can also play a role in the field of theoretical research in related fields. 1 the physicochemical properties of amoxicillin Amoxicillin (Amoxicillin, AMO) is a penicillin with amino side chains whose chemical structure is more than a hydroxyl group on the side chain benzene ring of AMP, both of which are similar in nature. AMO is a white crystalline powder, slightly bitter, slightly soluble in water, insoluble in ethanol, the specific rotation of +2900 ~ +3100. 2 the pharmacological mechanism of amoxicillin Antibacterial activity of AMO plays a major role in the basic structure of 6- aminopenicillanic acid in the beta lactam ring, can specificity and bacterial membrane target binding, inhibition of bacterial cell wall peptidoglycan synthase activity, thus preventing cell wall peptidoglycan synthesis, the bacterial cell wall defect, cell expansion cracking. 3 clinical application of amoxicillin The antibacterial effect of 3.1 antibacterial effect of antibacterial spectrum and the vast majority of bacteria in vitro and ampicillin, the same. But in Enterococcus and Salmonella effect is 2 times stronger than the latter, in addition, showed in vitro bactericidal and infection animal protection experiment, the product of a