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Transcranial Magnetic Stimulation and Aphasia (经颅磁刺激和失语症)
S26
SPECIAL COMMUNICATION
Transcranial Magnetic Stimulation and Aphasia Rehabilitation
Margaret A. Naeser, PhD, Paula I. Martin, BS, Michael Ho, PhD, Ethan Treglia, MS, CCC-SLP,
Elina Kaplan, BS, Shahid Bashir, PhD, Alvaro Pascual-Leone, MD, PhD
ABSTRACT. Naeser MA, Martin PI, Ho M, Treglia E, ment, and review a related functional magnetic resonance
Kaplan E, Bashir S, Pascual-Leone A. Transcranial magnetic (fMRI) study. In part 2, we briefly review a case study where
stimulation and aphasia rehabilitation. Arch Phys Med Rehabil TMS was combined with constraint-induced language therapy
2012;93(1 Suppl 1):S26-34. (CILT). In part 3, we conclude with a review of possible
mechanisms underlying language improvement post-TMS.
Repetitive transcranial magnetic stimulation (rTMS) has TMS is a noninvasive procedure that uses magnetic fields to
been reported to improve naming in chronic stroke patients create electric currents in discrete brain areas.3,4 TMS involves
with nonfluent aphasia since 2005. In part 1, we review the discharging a current through a coil of copper wire that is held
rationale for applying slow, 1-Hz, rTMS to the undamaged over the subject’s scalp. The current pulse flowing through the
right hemisphere in chronic nonfluent aphasia patients after a coil generates a rapidly fluctuating magnetic field that pene-
left hemisphere stroke; and we present a transcranial magnetic trates the scalp and skull unimpeded, and induces a changing
stimulation (TMS) protocol used with these patients that is electrical field in
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