20 cases of idiopathic thrombocytopenic purpura prednisone combination therapy for multi-resistant the A prime ampeptidum,（20例特发性血小板减少性紫癜强的松联合治疗主要ampeptidum多药耐药,）.docVIP

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20 cases of idiopathic thrombocytopenic purpura prednisone combination therapy for multi-resistant the A prime ampeptidum,（20例特发性血小板减少性紫癜强的松联合治疗主要ampeptidum多药耐药,）.doc

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20 cases of idiopathic thrombocytopenic purpura prednisone combination therapy for multi-resistant the A prime ampeptidum,（20例特发性血小板减少性紫癜强的松联合治疗主要ampeptidum多药耐药,）

20 cases of idiopathic thrombocytopenic purpura prednisone combination therapy for multi-resistant the A prime ampeptidum, Author: Zhang rock Feng lead Overall Xiao, Ma Mingli Wang Xiuxia [Words] idiopathic thrombocytopenic purpura Keywords: idiopathic thrombocytopenic purpura; associated with; treatment 0 Introduction Idiopathic thrombocytopenic purpura (ITP for a variety of causes hemorrhagic disease [1,2]. Disease immune, 85% and 90% of the cases related to the platelet surface PAIgG PAIgM and PA-C3 increased platelet destruction rate and to reduce the degree of proportional we use strong Songane multi the anti A hormone and ampeptidum three drugs used in conjunction with treatment, and achieved good effect. 1 objects and methods 1.1 object in all cases in line with the 1986 First National Conference of Thrombosis and Hemostasis ITP revised diagnostic criteria: the treatment group: 20 (4 male and 20 females with a mean age 21 (14 to 54 years old. Initial treatment of 12 cases of retreatment 8 cases (all the strong pine efficacy and recurrence. duration of 0.5 to 2.5 (average 1.0a. before treatment platelet average of 31 (8 to 51) ?109 ?L-1 control group 23 (M 5 and 18 females with an average age of 23 (15 to 52 years old, are naive. duration of 0.5 to 2.3 (average 0.9) a pre-treatment platelet Mean for 33 (12 ~ 56 ?109 ?L-1. two groups of illness , age contrast no significant difference. 1.2 Methods The treatment group: more than anti-A prime 20mg, daily 2 times, the meals served 4 ~ 8wk. Ampeptidum 1.0g, 3 times a day, clothing was 8 wk. Prednisone 1mg ?kg -1 ?D-1, most daily 60mg morning serving Dayton, 2wk tapering maintain to disable the control group: strong pine 1 ~ 2mg ?kg -1 ?d-1 morning serving Dayton, 2wk followed by a according to platelet rising tapering maintain to be disabled. treatment weekly check blood and platelet, check the bone marrow, electrocardiogram, and liver and kidney function before and after treatment.