左金胶囊制备及溶出速率测定（Preparation and dissolution rate of Zuojin capsules preparation）.docVIP

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左金胶囊制备及溶出速率测定（Preparation and dissolution rate of Zuojin capsules preparation）.doc

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左金胶囊制备及溶出速率测定（Preparation and dissolution rate of Zuojin capsules preparation）

左金胶囊制备及溶出速率测定（Preparation and dissolution rate of Zuojin capsules preparation） Preparation and dissolution rate of Zuojin capsules preparation Update Date: 2010-08-12 hits: Jia Haiying, Jia Haibo, Aimin, Hao Yuying, Xu Jibin Abstract: with different excipients prepared 3 kinds of Zuojinwan capsule, and determine the in vitro dissolution rate, T50, Td and m. The results showed that the dissolution rate of the 3 capsules was different, and the dissolution rate of the capsules prepared with Rhizoma Coptidis residue as the excipient was the fastest. The variance analysis of in vitro release parameters showed that the dissolution rates of the 3 capsules were significantly different (P 0.01). Keywords Zuojin capsules; berberine hydrochloride; dissolution rate The, Preparation, of, Zuo, Jin, Capsule, and, the, Determination, of,, its, Dissolution, Rate Jia, Haiying, Jia, Haibo, Ai, Min, et, Al Inner, Mongolia, Medical, College, Huhhot 010059 Abstract Three kinds of Zuo Jin capsule have been designed and prepared with different adjuvants and their dissolution rates have been determined respectively, T50 Td, and were obtained. The results showed that dissolution rates of three kinds of capsule were different. The capsule which is prepared from the rhizome of Chinese boldthreads lees as a kind of adjuvant has the fastest dissolution rate. Statistical analysis showed that there was remarkable difference in dissolution rate for three capsules. Key, words, Zuo, Jin, capsule; Berberine hydrochloride; Dissolution rate Zuojinwan 1 is a commonly used traditional Chinese medicine, mainly for Shugan Xiehuo, and stomach pain, better efficacy. In order to further the development of medicine and give full play to the influence of pharmaceutical dosage forms of drug interactions, we will change the pill capsules, and different excipients prepared 3 kinds of Zuojinwan capsule, and the dissolution rate were determined. The results showed that the dissolution rate of capsule prepared with R