about ofloxacin injection cefoperazone sodium injection incompatibility exists（对氧氟沙星注射头孢哌酮钠注射不相容的存在）.docVIP

About ofloxacin injection cefoperazone sodium injection incompatibility exists [Keywords] ofloxacin [Keywords] ofloxacin, cefoperazone sodium, incompatibility Ofloxacin third generation Quinolone antibiotics, it can affect its synthesis by inhibiting DNA gyrase, dual bactericidal effect, is a highly effective broad-spectrum antibiotics. Department of cefoperazone sodium third-generation cephalosporins against Gram positive and gram-negative bacteria have antibacterial activity [1] lt;lt; intravenous drug incompatibility table gt;gt; two drugs not be found in the meantime there are incompatibility, we found that in clinical work, ofloxacin injection Cefoperazone Sodium Injection incompatibility exists between the report are as follows. 1 Materials and Methods 11 reagent preparation Analog commonly used clinical concentration: 09% sodium chloride solution and 50 ml + cefoperazone sodium and 1 g preparation Cefoperazone Sodium Injection of 2%; 5% glucose injection 100 ml + ofloxacin 22 g preparation ofloxacin injection of 02% . 12 analog intravenous method 5% glucose injection 100 ml + a Ofloxacin of 02 g and 09% sodium chloride solution and 50 ml + cefoperazone sodium and 1 g does venipuncture first drops of ofloxacin injection, after drops of Cefoperazone Sodium Injection, which trickle one drop, is it immediately drops Tsubouchi white, continue to trickle 10 s after Murphy drops Tsubouchi liquid white milk samples, 1 min after the infusion tube all white floc save after 24 h of the infusion tube floc The substance still exist. the change trickle sequence, the first drops of to cefoperazone sodium injection, after drops of ofloxacin injection results are still the same. 13 test tube Take ofloxacin injection with a dropper and cefoperazone sodium injection, depending on the trickle dose, mixed observed phenomenon as follows: ① first test tube: Take ofloxacin injection 1 ml trickle Cefoperazone Sodium Injection 1 vitro ml, instillati