analysis of 28 cases and immunohistochemical seronegative hepatitis（分析28例和免疫组织化学血清反应阴性的肝炎）.docVIP

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analysis of 28 cases and immunohistochemical seronegative hepatitis（分析28例和免疫组织化学血清反应阴性的肝炎）.doc

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analysis of 28 cases and immunohistochemical seronegative hepatitis（分析28例和免疫组织化学血清反应阴性的肝炎）

Analysis of 28 cases and immunohistochemical seronegative hepatitis [Keywords:], hepatitis Keywords: hepatitis, viral; serology; immunohistochemistry 0 Introduction Found in the process of hepatitis etiological diagnosis, a considerable part of the hepatitis patients whose serology negative (non A - non-HGV now department treated 28 cases of non-A - Hepatitis G Clinical and immunohistochemical results reported below . 1 objects and methods 1.1 objects in this group, 28 (19 men and 9 females, aged 9 to 60 years old, with an average of 32.5 years old. Hepatitis history of familial aggregation, no history of blood transfusion, drinking history, taking the loss the liver drug history and the history of exposure to toxic acute hepatitis 12 national infectious cases (six cases of acute jaundice hepatitis, chronic hepatitis, 12 cases (9 cases with mild to severe cases. subacute severe hepatitis cases, 2 cases of chronic severe hepatitis and cirrhosis one cases of clinical diagnosis of 1995 parasite Conference revised standard. clinical manifestations have different levels of fatigue, loss of appetite, bloating and other symptoms. fever six cases and 14 cases, jaundice, hepatomegaly 6 cases, 11 cases of splenomegaly. liver function TBi lt;17.1μmol · L-1 14 cases, 17.1 85.5μmol · L-1 7 cases, 85.5 171μmol · L-3 cases, greater than 171μmol · L-1 4 cases normal ALT 6 cases, more than 10 cases less than 5 times the normal 5 to 10 times greater than 10 times the six cases of PTA (prothrombin activity) normal 11 cases, 80% to 60% of the 10 cases, 60% to 40% of the five cases, less than 40% of the two cases. all patients with HAV-HGV serum markers (including of HBV DNA, HCV RNA and HGV RNA negative, anti-EBV-IgM anti-CMV-IgM and anti-nuclear antibody anti-kidney microsomal antibody negative. erythrocyte sedimentation rate, serum urine copper normal. 1.2 Methods 1.2.1 Specimen Source by Menhgini method puncture of liver tissue, formalin-fixed specimens, emb