疏血通对糖尿病肾病地保护作用与对TGF-β1、TNF-α、IL-6与MCP-1地影响.pdfVIP

疏血通对糖尿病肾病的保护作用及对TGF-B l、TNF-o、m巧及McP—l的影响 英文摘要 The effectof on diabetic protectiveShuxuetong early andthe of on nephropathyimpactShuxuetongTGF-帚I、 TNF吨、IL-6andMCP-1 ABSTRACT To observethe of on diabetic Objective protectionShuxuetongearly nephropathy andthe of onthelevelsof MCP-1 impact TGF-争I、T】师吨、儿击、and Shuxuetong Methods60 with 2 selectedforthis patientstypediabetes(DM)werestudy, 30 with diabetes 2 without 30 including microalbminuria(DM patientstype group)and with diabetic 20 wereusedas patientsearly group)．andhealthysubjects nephropathy(DN control DN of andDM wereadministeredwith group(NCgroup)．’nlesubjects group asacourseof onconventionalof Shuxuetong(8IIll)，QD，14days treatment，based therapy DM．Thelevelsofserum necrosisfactor-口 transforminggrowthfactor-f31(TGF-{It)、tumor chemoattractant 仃NF吨)、interleukin-6(m-6)、urinarymonocyte protein-1(MCP一1)、 and albminandurinecreatininefor24 their urinary hours(calculatedratio)(UALB／Cr) were measuredbeforeandaftertreatmentasmain levelsofserumcreatinine tar