association of promoter methylation with histologic type and pleural indentation in non-small cell lung cancer (nsclc)协会启动子甲基化与组织学类型和胸膜凹陷在非小细胞肺癌(nsclc).pdfVIP

Ji et al. Diagnostic Pathology 2011, 6:48 /content/6/1/48 RESEARCH Open Access Association of promoter methylation with histologic type and pleural indentation in non-small cell lung cancer (NSCLC) Meiju Ji1†, Yong Zhang2†, Bingyin Shi1 and Peng Hou1* Abstract Background: Lung cancer is a major cause of death worldwide. Gene promoter methylation is a major inactivation mechanism of tumor-related genes, some of which can be served as a biomarker for early diagnosis and p