ginkgo biloba extract on aging red cell membrane atpase sod and mda impact（银杏叶提取物老龄红细胞膜atp酶sod和mda的影响）.docVIP

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ginkgo biloba extract on aging red cell membrane atpase sod and mda impact（银杏叶提取物老龄红细胞膜atp酶sod和mda的影响）.doc

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ginkgo biloba extract on aging red cell membrane atpase sod and mda impact（银杏叶提取物老龄红细胞膜atp酶sod和mda的影响）

Ginkgo biloba extract on aging red cell membrane ATPase SOD and MDA impact To write papers network: [Abstract] Objective To observe the ginkgo biloba extract (EGb761 under aging of the erythrocyte membrane adenosine triphosphatase (ATPase and superoxide dismutase (SOD and malondialdehyde (MDA content changes, explore EGb761 anti-aging mechanism. Constant temperature water bath Incubation simulate the natural aging process of red blood cells, observed EGb761 on the aging of the erythrocyte membrane MDA content, SOD and ATPase activity. results compared with the aging group, the effect of EGb761 group erythrocyte MDA decreased significantly, the activities of SOD, ATPase activity was significantly increased, the difference highly significant (t = 2.02 ~ 70.06, P lt;0.05,0.001. conclusion EGb761 could improve the antioxidant capacity of red blood cells to protect the erythrocyte membrane protein slow down the red blood cell aging process. [Keywords:] ginkgo biloba extract red cell membrane superoxide dismutase malondialdehyde [ABSTRACT] ObjectiveTo observe the effects of Ginkgo biloba extracts (EGb761) on erythrocyte survival, and explore the protective mechanism of EGb761 on erythrocyte.MethodsAfter 24 hours’ incubation in thermostatic waterbath, the concentration of the product of erythrocyte lipid peroxidation-malondialdehyde (MDA ) and the activity of superoxide dismutase (SOD) and ATPase in RBC were measured.ResultsCompared with the aging group, EGb761 could significantly decrease the erythrocyte MDA concentration and improve the activity of SOD and ATPase (t = 2.02-70.06; P lt;0.05, 0.001). ConclusionEGb761 can directly resist the erythrocyte membrane lipid peroxidation injury from aging. [KEY WORDS] Ginkgo biloba extracts; Erythrocyte membrane; Superoxide dismutase; Malondialdehyde In recent years, the ginkgo biloba extract (EGb761), a full range of research, research on the pharmacological effects of its main active ingredients of Ginkgo b