hematopoietic stem cell transplantation for treatment of autoimmune diseases 4 cases（造血干细胞移植用于治疗自身免疫性疾病4例）.docVIP

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hematopoietic stem cell transplantation for treatment of autoimmune diseases 4 cases（造血干细胞移植用于治疗自身免疫性疾病4例）.doc

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hematopoietic stem cell transplantation for treatment of autoimmune diseases 4 cases（造血干细胞移植用于治疗自身免疫性疾病4例）

Hematopoietic stem cell transplantation for treatment of autoimmune diseases 4 cases Author: Li-Ming Wang Ya-Hong Wang Xiaoyan Lu Hung [Keywords:] hematopoietic stem cell transplantation for autoimmune diseases 1 clinical data Example 1, the patient, male, 26-year-old with left ptosis six months due to decreased visual acuity, admission 20,040,218 neostigmine test and muscle fatigue test positive after admission, the diagnosis of myasthenia gravis (MG. with methyl bromide. neostigmine and prednisone can be briefly and relieve symptoms, but a short time of recurrent disease. 200,405 for treatment after transplantation compared with the previous left ptosis markedly improved, lower extremity weakness disappeared. follow-up 2 a patient do not need drugs to maintain able to participate in basketball and other sports. Example 2 patients, female, 48 years old. Suffering from SLE and lupus nephritis 14 a, continuous urinary protein  ~ , joint pain, lower limb edema aggravated six months, the therapeutic effect of dawn cricket, hydroxyl chloro-quinoline, etc. are not ideal. NAN, anti-dsDNA antibody (+) 200 505 APBSCT treatment of urinary protein disappeared, joint pain, lower extremity edema symptoms, autoantibodies (- follow-up so far when urine protein + significantly improved the quality of life. Example 3, the patient, female, aged 30, suffering from SLE and lupus nephritis 8 years because of anemia, splenomegaly, joint pain aggravated 2 months to our hospital on 200 601, check the time of admission Hb 78 g / L, splenomegaly 8.0 cm, moderate texture, urinary protein , autoantibodies NAN, anti-dsDNA antibody (+ after APBSCT treatment 1 mo of Hb rise up to 9 g / L, spleen retraction to 4.0 cm, the urine protein negative, symptoms reduce the discharge, follow-up since Hb 116 g / L, splenomegaly 2.5 cm, urine protein + -. Example 4, the patient, male, aged 46, suffering from SLE and lupus nephritis 20 a recurrence may be associated with lup