fluvoxamine treatment of obsessive-compulsive disorder clinical analysis(氟伏沙明治疗强迫症的临床分析).docVIP
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fluvoxamine treatment of obsessive-compulsive disorder clinical analysis(氟伏沙明治疗强迫症的临床分析)
Fluvoxamine treatment of obsessive-compulsive disorder clinical analysis
[Abstract] Objective To investigate the treatment of obsessive-compulsive disorder fluvoxamine efficacy and safety. Way to meet the enrollment criteria, 65 patients were randomly divided into treatment group, 32 cases of oral fluvoxamine 50-200mg / d, control group 33 cases, oral clomipramine 50-200mg / d. 8 weeks. Before treatment and after treatment 1,2,4,8 weekend Yale-Brown obsessive-compulsive disorder using Scale (Y-BOCS) to assess the clinical results between two groups rather, the difference was not significant. Fluvoxamine adverse reactions are mild and resistance by good Conclusion fluvoxamine safe and effective treatment of obsessive-compulsive disorder.
[Keywords] obsessive-compulsive disorder Fluvoxamine Clomipramine In this study, clomipramine for the control of fluvoxamine in the treatment of obsessive-compulsive disorder efficacy and side effects in a prospective randomized open study reported the following:
Object and method 1.1 Object department in September 2009 to 2010 in our hospital in August or outpatient treatment of patients, in line with lt;lt;Chinese Classification and Diagnostic Criteria of Mental Disordersgt;gt; (CCMD-3) diagnostic criteria for obsessive-compulsive disorder, Yale - Brown Obsessive-compulsive disorder Scale (Y-BOCS)gt; l6 minutes, remove the brain organic diseases, serious physical illness, substance abuse and pregnant or lactating women, in line with the above age group were 65 cases of the conditions were divided into two groups: F V Sand that group (n = 32 cases), including 12 males and 20 females, aged 18-56 years (mean 32.6 + -11.9 years), duration (2.90 ?2.8) years, the clomipramine group (n = 33 cases), including 15 males and 18 females; aged 16-55 years (mean 32.2 + -12.5 years), du ration (3.2 + -3.3) years more than the difference between the two groups was not significant (Pgt; 0.05) .
1.2 Methods fluvoxamine group
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