原创力文档compliant gluten-free children with celiac disease an evaluation of psychological distress兼容的无谷蛋白腹腔疾病的孩子心理压力的评价.pdfVIP
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compliant gluten-free children with celiac disease an evaluation of psychological distress兼容的无谷蛋白腹腔疾病的孩子心理压力的评价
Mazzone et al. BMC Pediatrics 2011, 11:46
/1471-2431/11/46
RESEARCH ARTICLE Open Access
Compliant gluten-free children with celiac
disease: an evaluation of psychological distress
1* 1 2 1 2 1
Luigi Mazzone , Laura Reale , Massimo Spina , Manuela Guarnera , Elena Lionetti , Serena Martorana and
Domenico Mazzone1
Abstract
Background: Children with chronic illnesses are known to have increased risks for emotional and behavioral
problems. In the present study, children and adolescent suffering from celiac disease (CD) were compared with
healthy controls to assess differences in the psychological profile.
Methods: A total of 100 well-treated and compliant CD patients (65 females/35 males; age mean ± SD: 10.38 ±
2.71) were compared to 100 normal controls (58 females/42 males; age mean ± SD: 11.47 ± 2.61). Emotional and
behavioral problems were assessed by the Child Behavior Checklist (CBCL), the Children’s Depression Inventory
(CDI) and the Multidimensional Anxiety Scale for Children (MASC).
Results: Subjects with CD self-reported an increased rate of anxiety and depression symptoms and showed higher
scores in “harm avoidance” and “somatic complaints”, in the CBCL parent-report questionnaire, as compared to
healthy control subjects. Furthermore, gender differences could be observed in the group of CD patients, with
males displaying significantly higher CBCL externalizing scores, in social, thought and attention problems, as
compared to female, who in turns showed more prominent internalizing symptoms such as depression.
Conclusions: The increased rate of emotional and behavioral problems in children and adolescent with CD
emphasizes the importance of an early detection of ment
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