constituents from moghat, the roots of glossostemon bruguieri (desf.)选民从moghat的根源glossostemon bruguieri(desf)。.pdfVIP

Molecules 2003, 8, 614-621 molecules ISSN 1420-3049 Constituents from Moghat, the Roots of Glossostemon bruguieri (Desf.) Meselhy R. Meselhy * Department of Pharmacognosy, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt, Tel: (+20) 2-3624105, Fax: (+20) 2-3635140. * To whom correspondence should be addressed; e-mail: meselhyragab@ Received: 10 March 2003; in revised form: 27 May 2003 / Accepted: 25 July 2003 / Published: 31 July 2003 Abstract: The new biflavone moghatin (3″′-hydroxycupressuflavone) was isolated from Moghat, the dried peeled roots of Glossostemon bruguieri (Desf.), together with five known compounds: 4′-methoxyisoscutellargin, sesamin, chrysophanol, emodin and methoxyemodin (physcion). The structures of these compounds were assigned on the basis of spectroscopic data. Occurrence of these compounds in Moghat is reported here for the first time. Keywords Moghat, Glossostemon bruguieri, Sterculiaceae, biflavone, anthraquinone. Introduction Plants of the cacao family (Sterculiaceae) are trees, shrubs, or herbs comprising about 65 genera and 1,000 species that are further characterized by the presence of stellate hairs and, in most cases, mucilaginous sap [1]. Glossostemon bruguieri (Desf.), family Sterculiaceae, is a shrub with thick long tapering dark colored roots (70-100 cm in length and 5-8 cm in breadth) [1, 2]. G. bruguieri is native to Iraq and Iran, and was cultivated in Egypt for its edible roots a long time ago. The dried peeled roots of G. bruguieri (Desf.) (known in Arabic as Moghat) are used in folk medicine for the treat