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紫杉醇治疗晚期肿瘤53例(Paclitaxel in the treatment of advanced tumors in 53 cases)
紫杉醇治疗晚期肿瘤53例(Paclitaxel in the treatment of advanced tumors in 53 cases)
Paclitaxel in the treatment of advanced tumors in 53 cases
Update Date: 2011-01-22 Click: Lin Jun
A total of 53 cases of ovarian cancer and breast cancer were treated with paclitaxel, and single drug therapy group and combined chemotherapy group were used to compare the efficacy of blood stasis and paclitaxel in the treatment of advanced cancer. Results: the effective rate of single drug therapy was 36.4% in ovarian cancer and 56.2% in breast cancer. The effective rate of combined chemotherapy was 58.3% in ovarian cancer and 42.8% in breast cancer. These results indicate that paclitaxel is effective in the treatment of advanced tumors.
Keywords Paclitaxel; advanced tumor; curative effect;
The yew is an effective component extracted from or extracted from the trunk, bark and needles of yew. Because of its unique mechanism of action and resistance to drug-resistant cells, it has received extensive attention in recent years. It is mainly involved in the microtubule / tubulin system and inhibits microtubule depolymerization, resulting in abnormal arrangement of microtubule bundles [1]. In order to observe the curative effect and side effect of paclitaxel, we performed clinical tests on 53 patients from 1996-07 to 1997-10. The results were reported as follows.
1 case selection
Of the 53 cases, aged 37 to 65 years old, average 55 + 6.4 years, confirmed by pathology or cytology were objective, observation index, liver and kidney function and normal blood, within the past 1 months has not made chemotherapy and other anti-tumor therapy, KPS 60 points, is expected to survive more than 3 months and observable indicators of hospitalization in patients with advanced. Among them, 23 cases of ovarian cancer, 30 cases of breast cancer. The clinical stages were stage III to iv..
2 treatment
Before use, ask the patient if there is any history of allergies, and check the white blood cell and platelet counts. Hav
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