adaptive computation of multiscale entropy and its application in eeg signals for monitoring depth of anesthesia during surgery自适应多尺度熵的计算及其应用在手术过程中麻醉深度监测脑电图信号.pdfVIP

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adaptive computation of multiscale entropy and its application in eeg signals for monitoring depth of anesthesia during surgery自适应多尺度熵的计算及其应用在手术过程中麻醉深度监测脑电图信号.pdf

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adaptive computation of multiscale entropy and its application in eeg signals for monitoring depth of anesthesia during surgery自适应多尺度熵的计算及其应用在手术过程中麻醉深度监测脑电图信号

Entropy 2012, 14, 978-992; doi:10.3390/ OPEN ACCESS entropy ISSN 1099-4300 /journal/entropy Article Adaptive Computation of Multiscale Entropy and Its Application in EEG Signals for Monitoring Depth of Anesthesia During Surgery Quan Liu 1, Qin Wei 1, Shou-Zen Fan 2, Cheng-Wei Lu 3,5, Tzu-Yu Lin 3,5, Maysam F. Abbod 4 and Jiann-Shing Shieh 5,* 1 School of Information Engineering, Wuhan University of Technology, Wuhan, 430070, China; E-Mails: quanliu@ (Q.L.); zivaw2010@ (Q.W.) 2 Department of Anesthesiology, College of Medicine, National Taiwan University, Taipei, 100, Taiwan; E-Mail: shouzen@ 3 Department of Anesthesiology, Far Eastern Memorial Hospital, Ban-Chiao, 220, Taiwan; E-Mails: drluchengwei@ (C.-W.L.); drlin1971@ (T.-Y.L.) 4 School of Engineering and Design, Brunel University, London, UB8 3PH, UK; E-Mail: maysam.abbod@brunel.ac.uk 5 Department of Mechanical Engineering, Yuan Ze University, Taoyuan, Chung-Li, 32003, Taiwan * Author to whom correspondence should be addressed; E-Mail: jsshieh@.tw; Tel.: +886-3-463-8800 (ext. 2470); Fax: +886-3-455-8013. Received: 29 March 2012; in revised form: 9 May 2012 / Accepted: 21 May 2012 / Published: 25 May 2012 Abstract: Entropy as an estimate of complexity of the electroencephalogram is an effective parameter for monitoring the depth of anesthesia (DOA) during surgery. Multiscale entropy (MSE) is useful to evaluate the complexity of signals over different time scales. However, the limitation of the length of processed signal is a problem due to observing the variati