原创力文档rapid assessment of malaria transmission using age-specific sero-conversion rates快速评估使用sero-conversion年龄的疟疾传播.pdfVIP
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rapid assessment of malaria transmission using age-specific sero-conversion rates快速评估使用sero-conversion年龄的疟疾传播
Rapid Assessment of Malaria Transmission Using Age-
Specific Sero-Conversion Rates
1,2 1,3 4 3 1,2 3
Laveta Stewart , Roly Gosling , Jamie Griffin , Samwel Gesase , Joseph Campo , Ramadan Hashim ,
3 3 5,6 5,6 1 1,7
Paul Masika , Jacklin Mosha , Teun Bousema , Seif Shekalaghe , Jackie Cook , Patrick Corran , Azra
4 1 1,2
Ghani , Eleanor M. Riley , Chris Drakeley *
1 Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom, 2 Joint Malaria Programme, Moshi,
Tanzania, 3 KILI-IPTi Project, JMP, Korogwe, Tanzania, 4 MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial
College, London, United Kingdom, 5 Kilimanjaro Christian Medical College, Tumaini University, Moshi, Tanzania, 6 Department of Medical Microbiology, Radboud
University Nijmegen Medical Centre, Nijmegen, The Netherlands, 7 Biotherapeutics Group, NIBSC, South Mimms, Herts, United Kingdom
Abstract
Background: Malaria transmission intensity is a crucial determinant of malarial disease burden and its measurement can
help to define health priorities. Rapid, local estimates of transmission are required to focus resources better but current
entomological and parasitological methods for estimating transmission intensity are limited in this respect. An alternative is
determination of antimalarial antibody age-specific sero-preval
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