rapid diagnostic algorithms as a screening tool for tuberculosis an assessor blinded cross-sectional study快速诊断算法作为结核病的筛查工具的评估员蒙蔽的横断面研究.pdfVIP

Rapid Diagnostic Algorithms as a Screening Tool for Tuberculosis: An Assessor Blinded Cross-Sectional Study 1,2 3 4 1 Franz Ratzinger , Harald Bruckschwaiger , Martin Wischenbart , Bernhard Parschalk , 5 1 6 1 1 Delmiro Fernandez-Reyes , Heimo Lagler , Alexandra Indra , Wolfgang Graninger , Stefan Winkler , Sanjeev Krishna7, Michael Ramharter1,8* 1 Division of Infectious Diseases and Tropical Medicine, Department of Medicine I, Medical University Vienna, Vienna, Austria, 2 Department of Laboratory Medicine, ¨ Medical University Vienna, Vienna, Austria, 3 Department of Internal Medicine, Krankenhaus der Barmherzigen Bruder, Vienna, Austria, 4 Information Systems Group, Institute of Bioinformatics, Johannes Kepler University, Linz, Austria,, 5 Division of Parasitology, National Institute for Medical Research, London, United Kingdom, 6 Austrian Agency for Health and Food Safety, Vienna, Austria, 7 Centre for Infection, St. George’s University of London, London, United Kingdom, 8 Institute for Tropical ¨ ¨ Medicine, University of Tubingen, Tubingen, Germany Abstract Background: A major obstacle to effectively treat and control tuberculosis is the absence of an accurate, rapid, and low-cost diagnostic tool. A new approach for the screening of patients for tuberculosis is the use of rapid diagnostic classification algorithms. Methods: We tested a previously published diagnostic algorithm based on