secrets of soil survival revealed by the genome sequence of arthrobacter aurescens tc1土壤生存的秘密揭示基因组序列的节细菌属aurescens tc1.pdfVIP

Secrets of Soil Survival Revealed by the Genome Sequence of Arthrobacter aurescens TC1 1[ 2,3[ 1 1 1 Emmanuel F. Mongodin , Nir Shapir , Sean C. Daugherty , Robert T. DeBoy , Joanne B. Emerson , 1 1 1 1 1 1 Alla Shvartzbeyn , Diana Radune , Jessica Vamathevan , Florenta Riggs , Viktoria Grinberg , Hoda Khouri , Lawrence P. Wackett2,3, Karen E. Nelson1¤, Michael J. Sadowsky2,3* 1 The Institute for Genomic Research, Rockville, Maryland, United States of America, 2 The BioTechnology Institute, University of Minnesota, St. Paul, Minnesota, United States of America, 3 Microbial and Plant Genomics Institute, University of Minnesota, St. Paul, Minnesota, United States of America Arthrobacter sp. strains are among the most frequently isolated, indigenous, aerobic bacterial genera found in soils. Member of the genus are metabolically and ecologically diverse and have the ability to survive in environmentally harsh conditions for extended periods of time. The genome of Arthrobacter aurescens strain TC1, which was originally isolated from soil at an atrazine spill site, is composed of a single 4,597,686 basepair (bp) circular chromosome and two circular plasmids, pTC1 and pTC2, which are 408,237 bp and 300,725 bp, respectively. Over 66% of the 4,702 open reading frames (ORFs) present in the TC1 genome could be assigned a putative function, and 13.2% (623 genes) appear to be unique to this bacterium, suggesting niche specialization. The genome of TC1 is most similar to that of Tropheryma, Leifsonia, Streptomyces, and Corynebacterium glutamicum, and analyses suggest that A. aurescens TC1 has expanded its metabolic abiliti