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Overview SGC - Structural Biology and Human Health: A New Approach to Publishing Structural Biology Results 1 ´ 1 2,3 1,4 Wen Hwa Lee *, Julian Atienza-Herrero , Ruben Abagyan , Brian D. Marsden 1 SGC, University of Oxford, Headington, Oxford, United Kingdom, 2 Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, United States of America, 3 Molsoft LLC, La Jolla, San Diego, California, United States of America, 4 Nuffield Department of Clinical Medicine University of Oxford, Headington, Oxford, United Kingdom The Structural Genomics Consortium case manner, with academic researchers the normal (or abnormal) functioning of (SGC) is a not-for-profit, public-private establishing specific protocols over a the human body and associated patho- partnership established to deliver novel relatively long period of time that are gens. In particular, this information pro- structural biology knowledge on proteins of difficult to implement or inappropriate for vides a better understanding of the basis medical relevance and place this informa- high-throughput approaches. As the se- by which different proteins achieve selec- tion into the public domain without restric- quencing of the human genome was tivity and specific binding to their cognate tion, spearheading the concept of ‘‘Open- completed the gap between known genes ligands and drugs [1]. Indeed, several Source Science’’ to enable drug discovery. and solved prot