银屑病患者伴代谢综合征的临床特点.pdfVIP

摘 要 银屑病患者伴有代谢综合征的临床特点 研究生：常远 导师：多兰·达力汗 副教授 摘 要 目的：回顾性分析银屑病伴有代谢综合征患者的临床特点。方法：对 182 例银 屑病患者进行问卷调查、体格检查和实验室检指标包括身高、体重、腰围、血压、 空腹血糖、甘油三酯、高密度脂蛋白和胆固醇。代谢综合征诊断标准采用 2005 年国 际糖尿病联盟制定的标准。比较伴有代谢综合征的银屑病患者(MS 组)与不伴有代谢 综合征的银屑病患者(非 MS 组) 的性别、年龄、发病年、病程、文化程度、家族遗传 史、生化指标及生活方式。结果： 182 例银屑病患者伴发代谢综合征者 68 例, 占 37.36% ；MS 组患者腰围、空腹血糖、甘油三酯、总胆固醇、血压均较非 MS 组明显 升高，高密度脂蛋白较非 MS 组患者低（P0.05 ）；MS 组患者较非 MS 组患者年龄 大，发病年龄晚、病程长 (P0.05) ；生活方式调查显示 MS 组吸烟、饮酒患者明显 多于非 MS 组(P0.05) 。结论：银屑病患者代谢综合征的发生率较高；伴有代谢综合 征的银屑病人年龄大、银屑病发病晚、病程长，与吸烟、饮酒等不良生活方式有关， 提示银屑病与代谢综合征有某些共同的发病基础。 关键词：银屑病；代谢综合征； 临床特点 —1— 新疆医科大学医学硕士学位论文 The clinical characteristics of patients with psoriasis associated with metabolic syndrome Postgraduate: Chang Yuan Supervisor: Associated Professor DuoLan.dalihan Abstract Objective: To analyze retrospectively the prevalence of metabolic syndrome (MS) in patients with psoriasis, and explore the clinical features of the patients with metabolic syndrome associated psoriasis.Methods:182 patients with psoriasis were investigated by face-to-face questionnaire, physical and laboratory examinations. Information included age, sex, the age of onset, duration of the disease, family history, education level, waistline, fasting plasma glucose (FPG), triglyceride (TC), high-density lipoprotein cholesterol (HDL-C) and blood pressure (BP). The diagnosis of MS was established according to the criteria of International Diabetes Federation. Results:①Of 182 patients with psoriasis, 68 suffered from metabolic syndrome, accounting for 37.36%.②The patients with metabolic syndrome-associated psoriasis always had significantly higher aver