呋喃妥因片(nitrofurantoin tablets)（呋喃妥因片 (nitrofurantoin tablets)）.docVIP

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呋喃妥因片(nitrofurantoin tablets)（呋喃妥因片 (nitrofurantoin tablets)）.doc

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呋喃妥因片(nitrofurantoin tablets)（呋喃妥因片 (nitrofurantoin tablets)）

呋喃妥因片(nitrofurantoin tablets)（呋喃妥因片 (nitrofurantoin tablets)） Nitrofurantoin Tablets (Nitrofurantoin Tablets) (nitrofurantoin tablets) The main ingredients of this product are: furan and so on. [traits] This product is an enteric coated tablet, which is yellow after removing the coating. [pharmacology and toxicology] This product is antibacterial. Escherichia coli is sensitive to this product, Enterobacter aerogenes, Enterobacter cloacae, proteus, Klebsiella and other Enterobacteriaceae strains of the drug sensitive Pseudomonas aeruginosa are usually resistant to the chemicals. This product has antibacterial effect on Gram-positive bacteria such as enterococcus. The antibacterial activity of this product is not affected by the products of pus and tissue. It has stronger activity in acidic urine, and the mechanism of antibacterial action interferes with the oxidoreductase system in bacteria, thus blocking its metabolic process. [pharmacokinetics] The microcrystalline of this product is absorbed rapidly and completely in the small intestine, and the absorption of large crystalline type is slower. Taking the same amount of food increases the bioavailability of two crystalline forms. The concentration of serum is very low, and the concentration of urine is higher. This product can permeate placenta and blood cerebrospinal fluid barrier. The binding rate of serum protein was 60%. The blood elimination half-life (t1/2b) ranged from 0.3 to 1 hours. Glomerular filtration is the main excretory pathway, and a small amount is excreted and reabsorbed from renal tubules. 30% ~ 40% rapid excretion of urine by the prototype, large crystalline excretion slower. This product can also be excreted by bile and removed by dialysis. [indications] Acute and simple lower urinary tract infections caused by Escherichia coli, Enterococcus, Staphylococcus, Klebsiella and Enterobacter are also used for the prevention of urinary tract infection. [usage and dosage] Take orally 50 to 100mg once a