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8中 消化系统疾病(8 diseases of digestive system)
8中 消化系统疾病(8 diseases of digestive system)
The eighth chapter is the clinical pathological types of digestive system diseases
(f) general viral hepatitis
It is divided into two types: acute and chronic:
1. acute (common) hepatitis is the most common. Clinical according to the patient whether appear icteric, and cent is icteric type and without icteric two kinds. In our country, there is no jaundice type, and most of them are viral hepatitis B, and some of them are hepatitis C. Icteric hepatitis lesions slightly heavier, shorter duration, more common in type A, D and E hepatitis. The pathological changes of jaundice type and non icteric hepatitis are basically the same.
Pathological changes, macroscopic view of the liver, swelling, soft, smooth surface.
Liver cells under microscope extensive degeneration, and the cells showed edema, liver cell cytoplasm loose light staining and ballooning degeneration and liver cell volume increases, derangement of liver congestion, sinus pressure and narrow, cholestatic liver cells visible phenomenon. Necrosis of liver cells is mild, and punctate necrosis and eosinophilic corpuscles are found in hepatic lobules (Fig 8 - 6). Mild inflammatory cell infiltration can be seen in the hepatic lobules and the portal area. Jaundice type necrosis is often slightly heavier, and the bile duct often has cholestasis and bile plugs.
Clinical pathological relation is diffuse liver cell enlargement, which makes the volume of liver become bigger, and the membrane is tense, which leads to the pain of the liver area. Liver cell degenerative changes, causing liver enzymes in cells released into the blood, serum alanine aminotransferase (sGpT) increased, but also can cause a variety of abnormal liver function lesion severe jaundice.
The majority of the patients with hepatitis C were cured within 6 months. The necrosis of the liver cells could be completely regenerated and repaired. However, hepatitis B and C tend to recover slowly. Among them, hepatitis B
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