a biosegmentation benchmark for evaluation of bioimage analysis methodsbioimage biosegmentation基准评价分析方法.pdfVIP

BMC Bioinformatics BioMed Central Database Open Access A biosegmentation benchmark for evaluation of bioimage analysis methods Elisa Drelie Gelasca*, Boguslaw Obara, Dmitry Fedorov, Kristian Kvilekval and BS Manjunath Address: Center for Bio-Image Informatics, Electrical and Computer Engineering Department, University of California Santa Barbara (UCSB), CA 93106, USA Email: Elisa Drelie Gelasca* - elisa.drelie@; Boguslaw Obara - obara@; Dmitry Fedorov - fedorov@; Kristian Kvilekval - kris@; BS Manjunath - manj@ * Corresponding author Published: 1 November 2009 Received: 26 November 2008 Accepted: 1 November 2009 BMC Bioinformatics 2009, 10:368 doi:10.1186/1471-2105-10-368 This article is available from: /1471-2105/10/368 © 2009 Drelie Gelasca et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: We present a biosegmentation benchmark that includes infrastructure, datasets with associated ground truth, and validation methods for biological image analysis. The primary motivation for creating this resource comes from the fact that it is very difficult, if not impossible, for an end-user to choose from a wide range of segmentation methods available in the literature for a particular bioimaging problem. No single algorithm is likely to