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a compact phage display human scfv library for selection of antibodies to a wide variety of antigens人类scfv紧凑的噬菌体展示库选择的各种抗原的抗体
BMC Biotechnology BioMed Central
Research article Open Access
A compact phage display human scFv library for selection of
antibodies to a wide variety of antigens
1 1 1
Potjamas Pansri , Nanthnit Jaruseranee , Kuntalee Rangnoi ,
2 1
Peter Kristensen and Montarop Yamabhai*
Address: 1School of Biotechnology, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand
and 2Department of Molecular Biology, University of Aarhus, Science Park, DK-8000 Aarhus C, Denmark
Email: Potjamas Pansri - potjamas@; Nanthnit Jaruseranee - mnanth@; Kuntalee Rangnoi - unichan_k9@;
Peter Kristensen - pk@mb.au.dk; Montarop Yamabhai* - montarop@sut.ac.th
* Corresponding author
Published: 29 January 2009 Received: 14 August 2008
Accepted: 29 January 2009
BMC Biotechnology 2009, 9:6 doi:10.1186/1472-6750-9-6
This article is available from: /1472-6750/9/6
© 2009 Pansri et al; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: Phage display technology is a powerful new tool for making antibodies outside the
immune system, thus avoiding the use of experimental animals. In the early days, it was postulat
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