a comprehensive system for evaluation of remote sequence similarity detection一个全面的系统远程序列相似性检测的评价.pdfVIP

a comprehensive system for evaluation of remote sequence similarity detection一个全面的系统远程序列相似性检测的评价.pdf

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a comprehensive system for evaluation of remote sequence similarity detection一个全面的系统远程序列相似性检测的评价

BMC Bioinformatics BioMed Central Methodology article Open Access A comprehensive system for evaluation of remote sequence similarity detection 2,3 1 2 2 Yuan Qi , Ruslan I Sadreyev , Yong Wang , Bong-Hyun Kim and Nick V Grishin*1,2 Address: 1Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, 5323, Harry Hines Blvd, Dallas, TX 75390-9050, USA, 2Department of Biochemistry, University of Texas Southwestern Medical Center, 5323, Harry Hines Blvd, Dallas, TX 75390-9050, USA and 3Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA Email: Yuan Qi - yuan_qi@; Ruslan I Sadreyev - sadreyev@; Yong Wang - Yong.Wang9@UTS; Bong-Hyun Kim - kim@; Nick V Grishin* - grishin@ * Corresponding author Published: 28 August 2007 Received: 4 April 2007 Accepted: 28 August 2007 BMC Bioinformatics 2007, 8:314 doi:10.1186/1471-2105-8-314 This article is available from: /1471-2105/8/314 © 2007 Qi et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Accurate and sensitive performance evaluation is crucial for both effective development of better structure prediction methods based on sequence similarity, and for the comparative analysis

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