夏枯草丸治疗高血压病及对颈动脉内膜-中层厚度影响.docVIP

夏枯草丸治疗高血压病及对颈动脉内膜-中层厚度影响 　 作者：魏运湘 刘真 于慧卿 李武卫 王强 论文代写 【摘要】 目的 观察夏枯草丸 治疗 中医辨证为肝火上炎兼络脉郁滞型高血压病临床疗效及对颈动脉内膜中层厚度的 影响 。 方法 将高血压病患者80例随机分为2组。治疗组40例予夏枯草丸，每次1丸，每日2次口服。对照组40例予牛黄降压丸，每次1～2丸，每日2次口服。疗程均为8周。治疗前后检测颈动脉内膜中层厚度的变化。结果 治疗组总有效率92.5%，对照组总有效率72.5%，2组比较差异有统计学意义（P＜0.05）。治疗后2组颈动脉内膜中层厚度均有所下降，与本组治疗前比较差异有统计学意义（P＜0.05）。2组治疗后比较差异无统计学意义(P＞0.05)。结论 夏枯草丸能有效降低血压，并改善颈动脉内膜中层厚度。 论文代写 【关键词】 高血压病；中药疗法; 降压剂(中药)；治疗 应用 　　 　　【Abstract】 Objective To investigate the therapeutic effect of Xiakucao pill (XKCP) on hypertension and its effect on the intima-media thickness (IMT)of carotid arteries effect. Methods 80 patients with hypertension were randomly divided into two groups, the patients in treatment group took Xiakucaowan pill, whereas the patients in control group took Niuhuangjiangya pill, with a treatment course of 8 weeks for both groups. The blood pressure and IMT of carotid arteries were detected before and after treatment. Results The total effective rates in treatment group and control group were 92.5% and 72.5% respectively, there was a significant difference between two groups（P＜0.05）. IMT of carotid arteries in both groups was obviously decreased after treatment ,as compared with those before treatment(Plt;0.05).But there was no significant difference in IMT of carotid arteries between two groups before and after treatment (Plt;0.05). Conclusion XKCP can reduce blood pressure effectively and improve IMT of carotid arteries. 　　【Key words】 Hypertension; TCM therapy; Depressor(TCM);Treatment application 论文代写 　　高血压病是最常见的心血管疾病，发病率高，可引起心、脑、肾等脏器多种并发症。2005-10—2007-07，我们应用夏枯草丸治疗高血压病40例，并与牛黄降压丸治疗40例对照观察，现报告如下。 　　1 资料与方法 毕业论文 　　1.1 一般资料 全部80例均为本院心内科门诊患者，随机分为2组。治疗组40例，男22例，女18例；年龄51～77岁；病程（7.1±5.3）年。对照组40例，男20例，女20例；年龄52～76岁；病程（6.9±5.0）年。2组病例一般资料比较差异无统计学意义（P＞0.05），具有可比性。 　　1.2 诊断标准［1］ 收缩压≥18.7 kPa（140 mm Hg），或舒张压≥12 kPa（90 mm Hg）。经病史、体格检查、心电图（ECG）、24 h动态心电图监测及有关实验室检查，除外继发性高血压及合并严重心、脑、肾并发症患者。中医辨证分型为肝火上炎兼络脉郁滞型，表现为眩晕，头胀痛，每因烦劳恼怒而加剧，面红目赤，口苦口干，溲黄，便秘，心烦易怒，少寐多梦，舌红，苔黄，脉弦。