原创力文档a novel statistical method to estimate the effective snp size in vertebrate genomes and categorized genomic regions一种新的统计方法来估计有效snp在脊椎动物的基因组大小和分类的基因组区域.pdfVIP
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a novel statistical method to estimate the effective snp size in vertebrate genomes and categorized genomic regions一种新的统计方法来估计有效snp在脊椎动物的基因组大小和分类的基因组区域
BMC Genomics BioMed Central
Methodology article Open Access
A novel statistical method to estimate the effective SNP size in
vertebrate genomes and categorized genomic regions
1 1 1,2
Daekwan Seo , Cizhong Jiang and Zhongming Zhao*
1 2
Address: Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA 23298, USA and Center
for the Study of Biological Complexity, Virginia Commonwealth University, Richmond, VA 23284, USA
Email: Daekwan Seo - dseo@; Cizhong Jiang - cjiang@; Zhongming Zhao* - zzhao@
* Corresponding author
Published: 29 December 2006 Received: 31 July 2006
Accepted: 29 December 2006
BMC Genomics 2006, 7:329 doi:10.1186/1471-2164-7-329
This article is available from: /1471-2164/7/329
© 2006 Seo et al; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: The local environment of single nucleotide polymorphisms (SNPs) contains
abundant genetic information for the study of mechanisms of mutation, genome evolution, and
causes of diseases. Recent studie
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