a rapid genome-wide response to drosophila melanogaster social interactions快速全基因组应对黑腹果蝇的社会交往.pdfVIP

BMC Genomics BioMed Central Research article Open Access A rapid genome-wide response to Drosophila melanogaster social interactions Ginger E Carney Address: Department of Biology, Texas AM University, College Station, TX, USA Email: Ginger E Carney - gcarney@ Published: 22 August 2007 Received: 22 December 2006 Accepted: 22 August 2007 BMC Genomics 2007, 8:288 doi:10.1186/1471-2164-8-288 This article is available from: /1471-2164/8/288 © 2007 Carney; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: The actions and reactions integral to mate recognition and reproduction are examples of multifaceted behaviors for which we are only beginning to comprehend the underlying genetic and molecular complexity. I hypothesized that social interactions, such as those involved in reproductive behaviors, would lead to immediate and assayable changes in gene expression. Such changes may have important effects on individual reproductive success and fitness through alterations in physiology or via short-term or long-term changes in nervous system function. Results: I used Affymetrix Drosophila Genome arrays to identify genes whose expression profiles would chang