accuracy of advanced versus strictly conventional 12-lead ecg for detection and screening of coronary artery disease, left ventricular hypertrophy and left ventricular systolic dysfunction先进和严格的常规12导心电图检测的准确性和冠状动脉疾病的筛查,左心室肥大和左心室收缩功能障碍.pdfVIP

Schlegel et al. BMC Cardiovascular Disorders 2010, 10:28 /1471-2261/10/28 R E S E A R C H A R T I C L E Open Access Research article Accuracy of advanced versus strictly conventional 12-lead ECG for detection and screening of coronary artery disease, left ventricular hypertrophy and left ventricular systolic dysfunction 1 1 1 2 3 4 4 Todd T Schlegel* , Walter B Kulecz , Alan H Feiveson , E Carl Greco , Jude L DePalma , Vito Starc , Bojan Vrtovec , 5 5 6 7 8 9 M Atiar Rahman , Michael W Bungo , Matthew J Hayat , Terry Bauch , Reynolds Delgado , Stafford G Warren , Tulio Núñez-Medina 10 11 11 12 12 , Rubén Medina , Diego Jugo , Håkan Arheden and Olle Pahlm Abstract Background: Resting conventional 12-lead ECG has low sensitivity for detection of coronary artery disease (CAD) and left ventricular hypertrophy (LVH) and low positive predictive value (PPV) for prediction of left ventricular systolic dysfunction (LVSD). We hypothesized that a ~5-min resting 12-lead advanced ECG test (A-ECG) that combined results from both the advanced and conventional ECG could more accurately screen for these conditions than strictly conventional ECG. Methods: Results from nearly every conventional and advanced resting ECG parameter known from the literature to have diagnostic or predictive value were first retrospectively evaluated in 418 healthy controls and 290 patients with imaging-proven CAD, LVH and/or LVSD. Each ECG parameter was examined for potential inclusion within multi- p