actomyosin contractility controls cell surface area of oligodendrocytes肌动球蛋白收缩控制细胞表面面积少突胶质细胞.pdfVIP
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actomyosin contractility controls cell surface area of oligodendrocytes肌动球蛋白收缩控制细胞表面面积少突胶质细胞
BMC Cell Biology BioMed Central
Research article Open Access
Actomyosin contractility controls cell surface area of
oligodendrocytes
1 1,2 3 1,2
Angelika Kippert , Dirk Fitzner , Jonne Helenius and Mikael Simons*
Address: 1Max-Planck-Institute for Experimental Medicine, Hermann-Rein-Str. 3, Göttingen, Germany, 2Department of Neurology, Robert-Koch-
Str. 40, University of Göttingen, Göttingen, Germany and 3Deptartment of Cellular Machines, Biotechnology Center, University of Technology,
Tatzberg 47-51, Dresden, Germany
Email: Angelika Kippert - kipperta@web.de; Dirk Fitzner - d.fitzner@med.uni-goettingen.de; Jonne Helenius - jonne.helenius@biotec.tu-
dresden.de; Mikael Simons* - msimons@gwdg.de
* Corresponding author
Published: 25 September 2009 Received: 30 March 2009
Accepted: 25 September 2009
BMC Cell Biology 2009, 10:71 doi:10.1186/1471-2121-10-71
This article is available from: /1471-2121/10/71
© 2009 Kippert et al; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: To form myelin oligodendrocytes expand and wrap their plasma membrane multiple
times around an axon. How is this expansion controlled?
Results: Here we show that cell
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