an improved method for genome wide dna methylation profiling correlated to transcription and genomic instability in two breast cancer cell lines一种改进的全基因组dna甲基化分析方法相关的转录和在两个乳腺癌细胞系基因组不稳定性.pdfVIP

BMC Genomics BioMed Central Research article Open Access An improved method for genome wide DNA methylation profiling correlated to transcription and genomic instability in two breast cancer cell lines †1,7 †2,1,3,4 †2,3 1 3 Jian Li* , Fei Gao , Ning Li , Shengting Li , Guangliang Yin , Geng Tian2,3, Shangang Jia2,3, Kai Wang1,5,7, Xiuqing Zhang2,3, 6 1 1,3,7 Huanming Yang , Anders Lade Nielsen and Lars Bolund Address: 1Institute of Human Genetics, University of Aarhus, The Bartholin building, DK-8000, Aarhus C, Denmark, 2Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, 101300, PR China, 3Beijing Genomics Institute, Shenzhen, Guangdong, 518083, PR China, 4Graduate School of Chinese Academy of Sciences, Yuquan Road 19A, Beijing, 100039, PR China, 5Bioinformatics Research Center (BiRC), University of Aarhus, Hoegh-Guldergs Gade 10, Building 1090, DK-8000, Aarhus, Denmark, 6Beijing Genomics Institute, B6 Industrial Zone, Beijing, 101300, PR China and 7Danish Centre for Translational Breast cancer research (DCTB), Strandboulevarden 49, DK-2100, Copenhagen, Denmark Email: Jian Li* - jianl@humgen.au.dk ; Fei Gao - flys828@; Ning Li - lining@; Shengting Li - lishengting@; Guangliang Yin - yinguangliang@; Geng Tian - tiang@; Shangang Jia - jiashanggang@; Kai Wang - wangk@humgen.au.dk; Xiuqing Zhang - zhangxq@; Huanming Yang - yanghm@; Anders Lade Nielsen - aln@humgen.au.dk; Lars Bolund - bolund@humgen.au.dk * Corresponding author †Equal contributors Published: 13