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anenpi identification and annotation of analogous enzymesanenpi类似酶的识别和注释
BMC Bioinformatics BioMed Central
Software Open Access
AnEnPi: identification and annotation of analogous enzymes
1,2 1 1
Thomas D Otto* , Ana Carolina R Guimarães , Wim M Degrave and
Antonio B de Miranda 1
Address: 1Laboratory for Functional Genomics and Bioinformatics, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro, Brazil and 2Ataulpho de Paiva
Foundation, Rio de Janeiro, Brazil
Email: Thomas D Otto* - otto@fiocruz.br; Ana Carolina R Guimarães - carolg@fiocruz.br; Wim M Degrave - wdegrave@fiocruz.br; Antonio B de
Miranda - antonio@fiocruz.br
* Corresponding author
Published: 17 December 2008 Received: 12 May 2008
Accepted: 17 December 2008
BMC Bioinformatics 2008, 9:544 doi:10.1186/1471-2105-9-544
This article is available from: /1471-2105/9/544
© 2008 Otto et al; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: Enzymes are responsible for the catalysis of the biochemical reactions in metabolic
pathways. Analogous enzymes are able to catalyze the same reactions, but they present no
significant sequence similarity at the primary level, and possibly different tertiary structures as well.
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