原创力文档assessment of the proliferative, apoptotic and cellular renovation indices of the human mammary epithelium during the follicular and luteal phases of the menstrual cycle评估的增殖、凋亡和细胞改造人类乳腺上皮的指数在月经周期的卵泡和黄体的阶段.pdfVIP
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assessment of the proliferative, apoptotic and cellular renovation indices of the human mammary epithelium during the follicular and luteal phases of the menstrual cycle评估的增殖、凋亡和细胞改造人类乳腺上皮的指数在月经周期的卵泡和黄体的阶段
Available online /content/7/3/R306
Vol 7 No 3 Open Access
Research article
Assessment of the proliferative, apoptotic and cellular renovation
indices of the human mammary epithelium during the follicular
and luteal phases of the menstrual cycle
1 2 3 1
Maria Alicia H Navarrete , Carolina M Maier , Roberto Falzoni , Luiz Gerk de Azevedo Quadros ,
1 1 1
Geraldo R Lima , Edmund C Baracat and Afonso CP Nazário
1Department of Gyneology, Mastology Division, Federal University of São Paulo, São Paulo, Brazil
2Department of Neurosurgery, Stanford University School of Medicine, Stanford, California, USA
3APC Pathology, São Paulo, Brazil
Corresponding author: Maria Alicia H Navarrete, chile@
Received: 6 Jun 2004 Revisions requested: 6 Aug 2004 Revisions received: 8 Oct 2004 Accepted: 20 Dec 2004 Published: 16 Feb 2005
Breast Cancer Research 2005, 7:R306-R313 (DOI 10.1186/bcr994)
/content/7/3/R306
© 2005 Navarrete et al. licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/
2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Introduction During the menstrual cycle, the mammary gland Results The proliferation index (PI), defined as the number of Ki-
goes through sequential waves of proliferation and apoptosis.
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