原创力文档association of ctla-4 gene polymorphisms with sporadic breast cancer in chinese han populationctla-4协会与散发性乳腺癌基因多态性在中国汉族人群.pdfVIP
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association of ctla-4 gene polymorphisms with sporadic breast cancer in chinese han populationctla-4协会与散发性乳腺癌基因多态性在中国汉族人群
BMC Cancer BioMed Central
Research article Open Access
Association of CTLA-4 gene polymorphisms with sporadic breast
cancer in Chinese Han population
†1 †2 1 1 3
Lihong Wang , Dalin Li , Zhenkun Fu , Heng Li , Wei Jiang and
Dianjun Li*1
Address: 1Department of Immunology, Harbin Medical University, Harbin 150081, China, 2Department of Surgery, the Third Affiliated Hospital
of Harbin Medical University, Harbin 150081, China and 3Department of Bioinformatics, Harbin Medical University, Harbin 150081, China
Email: Lihong Wang - jiangwlh@; Dalin Li - lidalin1975@163.com; Zhenkun Fu - zhenkun_fu@;
Heng Li - 0213liheng@; Wei Jiang - jiangweilh@; Dianjun Li* - dianjunli@163.com
* Corresponding author †Equal contributors
Published: 10 September 2007 Received: 8 April 2007
Accepted: 10 September 2007
BMC Cancer 2007, 7:173 doi:10.1186/1471-2407-7-173
This article is available from: /1471-2407/7/173
© 2007 Wang et al; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: The host immunogenetic background plays an important role in the development
of breast cancer. Cytotoxic T-lymphocyte antigen-4 (CTLA-4) is a molecule expressed
predominantly on act
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