equipment review the success of early goal-directed therapy for septic shock prompts evaluation of current approaches for monitoring the adequacy of resuscitation设备检查早期目标导向治疗感染性休克的成功提示评价当前的方法监测复苏的充分性.pdfVIP

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equipment review the success of early goal-directed therapy for septic shock prompts evaluation of current approaches for monitoring the adequacy of resuscitation设备检查早期目标导向治疗感染性休克的成功提示评价当前的方法监测复苏的充分性.pdf

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equipment review the success of early goal-directed therapy for septic shock prompts evaluation of current approaches for monitoring the adequacy of resuscitation设备检查早期目标导向治疗感染性休克的成功提示评价当前的方法监测复苏的充分性

Available online /content/9/4/349 Review Equipment review: The success of early goal-directed therapy for septic shock prompts evaluation of current approaches for monitoring the adequacy of resuscitation 1 2 3 Scott R Gunn , Mitchell P Fink and Benjamin Wallace 1Departments of Critical Care Medicine and Emergency Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA 2Departments of Critical Care Medicine and Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA 3European Marketing Manager Critical Care, Edwards Lifesciences Corresponding author: Mitchell P Fink, finkmp@ Published online: 27 May 2005 Critical Care 2005, 9:349-359 (DOI 10.1186/cc3725) This article is online at /content/9/4/349 © 2005 BioMed Central Ltd See editorial, page 307 [/content/9/4/307] Abstract inflammatory response syndrome (SIRS) and a systolic blood A recent trial utilizing central venous oxygen saturation (SCVO2) as pressure below 90 mmHg (after a 30 ml/kg fluid challenge) or a resuscitation marker in patients with sepsis has resulted in its a blood lactate concentration of 4 mmol/l or greater resulted in inclusion in the Surviving Sepsis Campaign guidelines. We review a hospital mortality rate of 30.5%, which was significantly less the evidence behind SCVO2 and its relationship to previous trials of than the mortality rate (46.5%) in the cohort randomly assigned goal-directed therapy. We compare SCVO2 to other tools for to usual care. As a result of this single-center randomized trial, assessing the