high-molecular-weight hyaluronan – a possible new treatment for sepsis-induced lung injury a preclinical study in mechanically ventilated rats高分子量透明质酸u2014u2014一个可能的新治疗sepsis-induced肺损伤的临床前研究机械通风的老鼠.pdfVIP

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high-molecular-weight hyaluronan – a possible new treatment for sepsis-induced lung injury a preclinical study in mechanically ventilated rats高分子量透明质酸u2014u2014一个可能的新治疗sepsis-induced肺损伤的临床前研究机械通风的老鼠.pdf

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high-molecular-weight hyaluronan – a possible new treatment for sepsis-induced lung injury a preclinical study in mechanically ventilated rats高分子量透明质酸u2014u2014一个可能的新治疗sepsis-induced肺损伤的临床前研究机械通风的老鼠

Available online /content/12/4/R102 Vol 12 No 4 Open Access Research High-molecular-weight hyaluronan – a possible new treatment for sepsis-induced lung injury: a preclinical study in mechanically ventilated rats Yung-Yang Liu1,2,3,4, Cheng-Hung Lee1,2,5, Rejmon Dedaj1,2, Hang Zhao1,2, Hicham Mrabat1,2, Aviva Sheidlin6, Olga Syrkina1,2,7, Pei-Ming Huang1,2,8, Hari G Garg1,2, Charles A Hales1,2 and Deborah A Quinn1,2 1Pulmonary and Critical Care Unit, Department of Medicine, Massachusetts General Hospital, 55 Fruit Street Boston, MA 02114, USA 2Harvard Medical School, 25 Shattuck St, Boston, MA, 02115 USA 3Chest Department, Taipei Veterans General Hospital, Sec 2, Shih-Pai Rd, Taipei, 11217, Taipei, Taiwan 4National Yang-Ming University, School of Medicine, No.155, Sec.2, Linong Street, Taipei, 112 Taiwan 5Department of Internal Medicine, National Cheng Kung University Hospital, 138 Sheng-Li Road, Tainan, 70428 Taiwan 6Genzyme Corporation, 500 Kendall Street, Cambridge, MA 02142 USA 7Shriners Burn Hospital, 51 Blossom Street, Boston, MA 02114 USA 8Department of Traumatology and Surgery, National Taiwan University Hospital, No. 7, Chung-Shan S. Road, Taipei 100, Taiwan Corresponding author: Deborah A Quinn, dquinn1@ Received: 29 Mar 2008 Revisions requested: 8 May 2008 Revisions received: 14 Jun 2008 Accepted: 8 Aug 2008 Published: 8 Aug 2008 Critical Care 2008, 12:R102 (doi:10.1186/cc6982) This article is online at: /content/12/4/R102 © 2008 Liu et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is prope