hospital infection after major amputations医院感染后主要的截肢.pdfVIP

de Godoy et al. Annals of Clinical Microbiology and Antimicrobials 2010, 9:15 /content/9/1/15 R E S E A R C H Open Access Research Hospital infection after major amputations 1 2 2 José Maria Pereira de Godoy* , Janalice Vasconcelos Ribeiro , Lívia Andrioli Caracanhas and Maria de Fátima Guerreiro Godoy3 Abstract The aim of the current study was to evaluate the prevalence of stump infections after major amputations of the lower extremities. Patients rehospitalized in Hospital de Base of the Medicine School in São José do Rio Preto in the period from January 2005 to January 2007 due to stump infection after major amputations of lower extremities were evaluated in a retrospective study. All the patients underwent prophylactic antibiotic therapy at the time of the surgery. The Fisher exact test was utilized for statistical analysis with an alpha error of 5% (p-value 0.05) being considered acceptable. A total of 231 patients were submitted to major amputations during this period and 17 (7.3%) were rehospitalized due to amputation stump infections of which 5 (29.4%) died within one month. The association between death due to stump infection and other causes of death during rehospitalizations was not significant (Fisher exact test: p 0.1). However, death during rehospitalizations was significantly higher than in the initial hospitalization. Introduction Wound infection rates ranging from 13 to 40% have Chronic critical limb ischemia, defined as 2 weeks of been reported following major lower limb amputation [7- rest pain, ulcers, or tissue loss attributed to arterial occlu- 11]. Methici