joint genomic evaluation of french dairy cattle breeds using multiple-trait models联合基因法国奶牛品种使用multiple-trait模型的评价.pdfVIP

Karoui et al. Genetics Selection Evolution 2012, 44:39 Ge n e t i c s /content/44/1/39 Se l e c t i o n Evolution RESEARCH Open Access Joint genomic evaluation of French dairy cattle breeds using multiple-trait models 1* 1 1 2 Sofiene Karoui , María Jesús Carabaño , Clara Díaz and Andrés Legarra Abstract Background: Using a multi-breed reference population might be a way of increasing the accuracy of genomic breeding values in small breeds. Models involving mixed-breed data do not take into account the fact that marker effects may differ among breeds. This study was aimed at investigating the impact on accuracy of increasing the number of genotyped candidates in the training set by using a multi-breed reference population, in contrast to single-breed genomic evaluations. Methods: Three traits (milk production, fat content and female fertility) were analyzed by genomic mixed linear models and Bayesian methodology. Three breeds of French dairy cattle were used: Holstein, Montbéliarde and Normande with 2976, 950 and 970 bulls in the training population, respectively and 964, 222 and 248 bulls in the validation population, respectively. All animals were genotyped with the Illumina Bovine SNP50 array. Accuracy of genomic breeding values was evaluated under three scenarios for the correlation of genomic breeding values between breeds (rg): uncorrelated (1), rg = 0; estimated rg (2); high, rg = 0.95 (3). Accuracy and bias of predict