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moving beyond tight glucose control to safe effective glucose control超越严格血糖控制安全有效的血糖控制.pdf

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moving beyond tight glucose control to safe effective glucose control超越严格血糖控制安全有效的血糖控制

Available online /content/12/3/149 Commentary Moving beyond tight glucose control to safe effective glucose control James S Krinsley1 and Jean-Charles Preiser2 1Division of Critical Care, Stamford Hospital, 190 West Broad Street, Stamford, CT 06902, USA 2Department of General Intensive Care, University Hospital Centre of Liege, Domaine Universitaire de Liège, 4000 Liege, Belgium Corresponding author: Jean-Charles Preiser, Jean-Charles.Preiser@chu.ulg.ac.be Published: 16 May 2008 Critical Care 2008, 12:149 (doi:10.1186/cc6889) This article is online at /content/12/3/149 © 2008 BioMed Central Ltd Abstract central to TGC, with frequent assessment of glycemic levels The impressive benefits related to the use of tight glucose control and responding adjustments in the administered treatment. by intensive insulin therapy have not been reproduced until now in The experience and skill of the nursing staff in the use of multicenter large-scale prospective randomized trials. Although the protocols will materially affect the probability that the reasons for these failures are not entirely clear, we suggest the use treatment goals of the protocol are achieved. Moreover, the of a stepwise approach – Safe, Effective Glucose Control – that structural and organizational characteristics of the ICU may will essentially target an intermediate blood glucose level. As com- have a strong impact, especially in view of the high work pared with genuine tight glucose control, Safe, Effective Glucose Control –