原创力文档multifocal langerhans cell sarcoma involving epidermis a case report and review多病灶的涉及表皮朗格汉斯细胞肉瘤病例报告和审查.pdfVIP
- 1、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。。
- 2、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击 这里二次下载。
- 3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
- 4、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
- 5、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
- 6、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
- 7、VIP文档为合作方或网友上传，每下载1次， 网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档
查看更多
multifocal langerhans cell sarcoma involving epidermis a case report and review多病灶的涉及表皮朗格汉斯细胞肉瘤病例报告和审查
Wang et al. Diagnostic Pathology 2012, 7:99
/content/7/1/99
CASE REPORT Open Access
Multifocal Langerhans cell sarcoma involving
epidermis: a case report and review
1* 1 1 1 2
Changsong Wang , Yanping Chen , Chunfang Gao , Jian Yin and Hong Li
Abstract
Objective: To study the clinico-pathological characteristics of Langerhans cell sarcoma (LCS) which involving
epidermis.
Methods: A case of primary multifocal LCS was analyzed in histopathology and immunophenotype.
Results: A 41-year-old man with multifocal cutaneous LCS involving the inguina and waist was reported. Clinical
and pathology data were available. Neoplastic cells with markedly malignant cytological features were observed.
Tumor cells exhibited irregular shape with abundant and eosinophilic red staining cytoplasm; large,
irregular-shaped, showing lobulated or dented nucleus and some cells with a longitudinal nuclear groove and
prominent nucleoli. The tumor cells expressed CD1a, Langerin (CD207), S-100 protein, CD68 and vimentin, and did
not express pan-T or B cell markers and epithelial markers. The patient died less than 1 year after diagnosis due to
local recurrence and metastasis to the lung, despite the administration of local radiation and chemotherapy.
Conclusions: LCS is a tumor with markedly malignant cytological features that originates from Langerhans cells.
Primary multifocal neoplasms involving epidermis is even rare. Accurate diagnosis is based on the histopathological
and immunohistochemical of the tumor cells.
Virtual slide: The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/
1182345104754765.
Keywords: Langerhans cell sarcoma, Multiple focus, Langerin, CD1a
Background
您可能关注的文档
- modeling of nonlinear aggregation for information fusion systems with outliers based on the choquet integral信息融合系统的建模的非线性聚合与异常值基于·曲克积分.pdf
- mediated electron transfer at redox active monolayers. part 3 bimolecular outer-sphere, first order koutecky-levich and adduct formation mechanisms在单层氧化还原活性介导的电子转移。.pdf
- modeling relationships between calving traits a comparison between standard and recursive mixed models建模崩解特性之间的关系比较标准和递归的混合模型.pdf
- molecular and crystal structures of three berberine derivatives三个小檗碱衍生物的分子和晶体结构.pdf
- molecular biogeography of europe pleistocene cycles and postglacial trends欧洲分子生物地理学更新世周期和冰河期以后的趋势.pdf
- molecular iodine-mediated cyclization of tethered heteroatom-containing alkenyl or alkynyl systems系的分子iodine-mediated环合heteroatom-containing烯基或炔基系统.pdf
- mobilization of pro-inflammatory lipids in obese plscr3-deficient mice促炎脂质动员在肥胖plscr3-deficient老鼠.pdf
- molecular mechanism of ochratoxin a transport in the kidney赭曲霉毒素a的分子机制在肾脏内运输.pdf
- molecular mechanisms of spindle function轴功能的分子机制.pdf
- molecular mechanisms of autoimmunity triggered by microbial infection自身免疫的分子机制由微生物感染引起的.pdf
- multifocal erg wavelet packet decomposition applied to glaucoma diagnosis多病灶的erg小波包分解应用于青光眼的诊断.pdf
- multifamily group psychoeducation and cognitive remediation for first-episode psychosis a randomized controlled trial多户群体心理教育和认知矫正对首发精神病随机对照试验.pdf
- multifocal pecoma (pecomatosis) of the female genital tract and pelvis a case report and review of the literature多病灶的pecoma(pecomatosis)女性生殖道和骨盆病例报告和文献之回顾.pdf
- multi-component based cross correlation beat detection in electrocardiogram analysis多组分的基于互相关检测心电图分析.pdf
- multi-hop routing mechanism for reliable sensor computing种可靠的传感器计算路由机制.pdf
- multifunctional urban agriculture for sustainable land use planning in the united states多功能城市农业可持续土地利用规划在美国.pdf
- multifunctional nature of the arenavirus ring finger protein z多功能的沙粒病毒蛋白质z无名指.pdf
- multi-hop routing-based optimization of the number of cluster-heads in wireless sensor networks种routing-based优化无线传感器网络中簇首的数量.pdf
- multi-channel morphological profiles for classification of hyperspectral images using support vector machines多通道形态资料,使用支持向量机的高光谱图像分类.pdf
- multi-level modeling of social factors and preterm delivery in santiago de chile社会因素和多层次建模在智利圣地亚哥早产.pdf
文档评论（0）