multifocal erg wavelet packet decomposition applied to glaucoma diagnosis多病灶的erg小波包分解应用于青光眼的诊断.pdfVIP

Miguel-Jiménez et al. BioMedical Engineering OnLine 2011, 10:37 /content/10/1/37 RESEARCH Open Access Multifocal ERG wavelet packet decomposition applied to glaucoma diagnosis 1* 1 1 1 2 Juan M Miguel-Jiménez , Sergio Ortega , Luciano Boquete , José M Rodríguez-Ascariz and Román Blanco * Correspondence: Abstract jmanuel@depeca.uah.es 1Department of Electronics, Background: Glaucoma is the second-leading cause of blindness worldwide and University of Alcalá, 28701 Alcalá de Henares, Spain early diagnosis is essential to its treatment. Current clinical methods based on Full list of author information is multifocal electroretinography (mfERG) essentially involve measurement of available at the end of the article amplitudes and latencies and assume standard signal morphology. This paper presents a new method based on wavelet packet analysis of global-flash multifocal electroretinogram signals. Methods: This study comprised twenty-five patients diagnosed with OAG and twenty-five control subjects. Their mfERG recordings data were used to develop the algorithm method based on wavelet packet analysis. By reconstructing the third wavelet packet contained in the fourth decomposition level (ADAA4) of the mfERG recording, it is possible to obtain a signal from which to extract a marker in the 60-