noninvasive positive pressure ventilation for respiratory failure caused by exacerbations of chronic obstructive pulmonary disease a standard of care无创正压通气对呼吸衰竭引起的急性加重的慢性阻塞性肺疾病的标准治疗.pdfVIP

Critical Care December 2003 Vol 7 No 6 Hill Commentary Noninvasive positive pressure ventilation for respiratory failure caused by exacerbations of chronic obstructive pulmonary disease: a standard of care? Nicholas S Hill Pulmonary, Critical Care and Sleep Division, TUFTS – New England Medical Center, Boston, MA, USA Correspondence: Nicholas S Hill, nhill@ Published online: 30 May 2003 Critical Care 2003, 7:400-401 (DOI 10.1186/cc2335) This article is online at /content/7/6/400 © 2003 BioMed Central Ltd (Print ISSN 1364-8535; Online ISSN 1466-609X) Abstract This editorial comments on a meta-analysis of the use of noninvasive positive pressure ventilation to treat patients with acute respiratory failure caused by chronic obstructive pulmonary disease (COPD) exacerbations published in the British Medical Journal earlier this year. Based on its analysis of seven randomized controlled trials that met pre-specified criteria, the meta-analysis demonstrated highly significant benefits of noninvasive positive pressure ventilation in COPD patients, including a reduction in a combined end-point consisting of death and endotracheal intubation. The editorial argues that, based on the strength of this and other evidence, noninvasive positive pressure ventilation to treat selected patients with acute respiratory failure due to COPD exacerbations should now be considered a standard of care. Keywords acute respiratory failure, chronic obstructive pulmonary disease, COPD exacerbation,