原创力文档neurological abnormalities and neurocognitive functions in healthy elder people a structural equation modeling analysis神经系统异常和神经认知功能在健康的老人们一个结构方程建模分析.pdfVIP
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neurological abnormalities and neurocognitive functions in healthy elder people a structural equation modeling analysis神经系统异常和神经认知功能在健康的老人们一个结构方程建模分析
Chan et al. Behavioral and Brain Functions 2011, 7:32
/content/7/1/32
RESEARCH Open Access
Neurological abnormalities and neurocognitive
functions in healthy elder people: A structural
equation modeling analysis
1,2* 1,2,3 2 1,2,3 4 1,2,3 1,2,3
Raymond CK Chan , Ting Xu , Hui-jie Li , Qing Zhao , Han-hui Liu , Yi Wang , Chao Yan ,
Xiao-yan Cao1,2,3, Yu-na Wang1,2,3, Yan-fang Shi1,2 and Paola Dazzan5
Abstract
Background/Aims: Neurological abnormalities have been reported in normal aging population. However, most of
them were limited to extrapyramidal signs and soft signs such as motor coordination and sensory integration have
received much less attention. Very little is known about the relationship between neurological soft signs and
neurocognitive function in healthy elder people. The current study aimed to examine the underlying relationships
between neurological soft signs and neurocognition in a group of healthy elderly.
Methods: One hundred and eighty healthy elderly participated in the current study. Neurological soft signs were
evaluated with the subscales of Cambridge Neurological Inventory. A set of neurocognitive tests was also
administered to all the participants. Structural equation modeling was adopted to examine the underlying
relationship between neurological soft signs and neurocognition.
Results: No significant differences were found between the male and female elder people in neurocognitive
function performances and neurological soft signs. The model fitted well in the elderly and indicated the moderate
associations between neurological soft signs and neurocognition, specifically verbal memory, visual memory and
working memory.
Conclusions: The neurological so
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