原创力文档nutraceutical approach for preventing obesity-related colorectal and liver carcinogenesis营养食品的方法对预防肥胖引起的结肠直肠癌和肝脏致癌作用.pdfVIP
- 1、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。。
- 2、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击 这里二次下载。
- 3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
- 4、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
- 5、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
- 6、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
- 7、VIP文档为合作方或网友上传，每下载1次， 网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档
查看更多
nutraceutical approach for preventing obesity-related colorectal and liver carcinogenesis营养食品的方法对预防肥胖引起的结肠直肠癌和肝脏致癌作用
Int. J. Mol. Sci. 2012, 13, 579-595; doi:10.3390/ijm
OPEN ACCESS
International Journal of
Molecular Sciences
ISSN 1422-0067
/journal/ijms
Review
Nutraceutical Approach for Preventing Obesity-Related
Colorectal and Liver Carcinogenesis
Masahito Shimizu 1,*, Masaya Kubota 1, Takuji Tanaka 2 and Hisataka Moriwaki 1
1 Department of Medicine, Gifu University Graduate School of Medicine, Gifu 501-1194, Japan;
E-Mails: samurai0201@yahoo.co.jp (M.K.); hmori@gifu-u.ac.jp (H.M.)
2 The Tohkai Cytopathology Institute: Cancer Research and Prevention (TCI-CaRP),
Gifu 500-8285, Japan; E-Mail: takutt@toukaisaibou.co.jp
* Author to whom correspondence should be addressed; E-Mail: shimim-gif@umin.ac.jp;
Tel.: +81-58-230-6313; Fax: +81-58-230-6310.
Received: 28 November 2011; in revised form: 20 December 2011 / Accepted: 27 December 2011 /
Published: 5 January 2012
Abstract: Obesity and its related metabolic abnormalities, including insulin resistance,
alterations in the insulin-like growth factor-1 (IGF-1)/IGF-1 receptor (IGF-1R) axis, and
the state of chronic inflammation, increase the risk of colorectal cancer (CRC) and
hepatocellular carcinoma (HCC). However, these findings also indicate that the metabolic
disorders caused by obesity might be effective targets to prevent the development of
CRC and HCC in obese individuals. Green tea catechins (GTCs) possess anticancer and
您可能关注的文档
- non-invasive glucose measurement by use of metabolic heat conformation method非侵入式葡萄糖测量利用代谢热构造方法.pdf
- nonimmunoglobulin e-mediated immune reactions to foodsnonimmunoglobulin e-mediated免疫反应的食物.pdf
- non-invasive assessment of arterial stiffness using oscillometric blood pressure measurement非侵入性评估动脉硬化使用示波的血压测量.pdf
- non-invasive assessment of fluid responsiveness by changes in partial end-tidal co2 pressure during a passive leg-raising maneuver非侵入性评估流体响应的变化部分end-tidal二氧化碳压力在一个被动的腿抬高回旋余地.pdf
- non-invasive algorithm for bowel motility estimation using a back-propagation neural network model of bowel sounds非侵入性的肠道运动估计算法使用bp神经网络模型的肠的声音.pdf
- noninvasive biomarkers for the diagnosis of steatohepatitis and advanced fibrosis in nafld肝病的无创性诊断生物标记和先进的肝纤维化的非酒精性脂肪肝.pdf
- non-intrusive load monitoring approaches for disaggregated energy sensing a survey非侵入性的负载监测方法分解能量传感测量.pdf
- noninvasive method to estimate anaerobic threshold in individuals with type 2 diabetes非侵入性方法来估计无氧阈值在2型糖尿病患者.pdf
- noninvasive positive pressure ventilation for respiratory failure caused by exacerbations of chronic obstructive pulmonary disease a standard of care无创正压通气对呼吸衰竭引起的急性加重的慢性阻塞性肺疾病的标准治疗.pdf
- non-invasive mr imaging of inflammation in a patient with both asymptomatic carotid atheroma and an abdominal aortic aneurysm a case report非侵入性成像先生的炎症患者无症状的颈动脉粥样硬化和腹主动脉瘤病例报告.pdf
文档评论（0）