non-invasive assessment of arterial stiffness using oscillometric blood pressure measurement非侵入性评估动脉硬化使用示波的血压测量.pdfVIP
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non-invasive assessment of arterial stiffness using oscillometric blood pressure measurement非侵入性评估动脉硬化使用示波的血压测量
Komine et al. BioMedical Engineering OnLine 2012, 11:6
/content/11/1/6
RESEARCH Open Access
Non-invasive assessment of arterial stiffness using
oscillometric blood pressure measurement
*
Hidehiko Komine , Yoshiyuki Asai, Takashi Yokoi and Mutsuko Yoshizawa
* Correspondence: h-komine@aist. Abstract
go.jp
Human Technology Research Background: Arterial stiffness is a major contributor to cardiovascular diseases.
Institute, National Institute of
Advanced Industrial Science and Because current methods of measuring arterial stiffness are technically demanding,
Technology (AIST), Higashi 1-1-1, the purpose of this study was to develop a simple method of evaluating arterial
Tsukuba, Ibaraki 305-8566, Japan stiffness using oscillometric blood pressure measurement.
Methods: Blood pressure was conventionally measured in the left upper arm of 173
individuals using an inflatable cuff. Using the time series of occlusive cuff pressure
and the amplitudes of pulse oscillations, we calculated local slopes of the curve
between the decreasing cuff pressure and corresponding arterial volume. Whole
pressure-volume curve was derived from numerical integration of the local slopes.
The curve was fitted using an equation and we identified a numerical coefficient of
the equation as an index of arterial stiffness (Arterial Pressure-volume Index, API). We
also measured brachial-ankle (baPWV) PWV and carotid-femoral (cfPWV) PWV using a
vascular testing device
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