oral phosphatidylcholine pretreatment alleviates the signs of experimental rheumatoid arthritis口服磷脂酰胆碱预处理减轻实验性类风湿关节炎的迹象.pdf

Available online /content/11/2/R43 Vol 11 No 2 Open Access Research article Oral phosphatidylcholine pretreatment alleviates the signs of experimental rheumatoid arthritis 1,2 3 1 2 1 Gabor Erős , Saleh Ibrahim , Nikolai Siebert , Mihály Boros and Brigitte Vollmar 1Institute for Experimental Surgery, University of Rostock, Schillingallee 69a, Rostock D-18057, Germany 2Institute of Surgical Research, University of Szeged, Pécsi u. 6, Szeged H-6720, Hungary 3Immunogenetics Group, University of Rostock, Schillingallee 70, Rostock D-18057, Germany Corresponding author: Brigitte Vollmar, brigitte.vollmar@med.uni-rostock.de Received: 2 Dec 2008 Revisions requested: 18 Jan 2009 Revisions received: 16 Feb 2009 Accepted: 18 Mar 2009 Published: 18 Mar 2009 Arthritis Research Therapy 2009, 11:R43 (doi:10.1186/ar2651) This article is online at: /content/11/2/R43 © 2009 Erős et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Introduction Phosphatidylcholine and phosphatidylcholine- were determined, and classical histological analysis was derived metabolites exhibit anti-inflammatory properties in performed. various stress conditions. We hypothesized that dietary Results Phosphatidylcho